朝藿定A

分析标准品,HPLC≥98%

Epimedin A

CAS号：110623-72-8

分子式：C39H50O20

分子量：838.81

MDL：MFCD30496681

别名：淫羊霍定A; 朝藿定A;;1-Methoxy-10H-9-thia-2,4-diaza-phenanthren-3-ylamine

产品介绍

熔点：206-207℃

沸点：1099.831℃ at 760 mmHg

外观：棕黄色结晶粉末

溶解性：Methanol  :  62.5  mg/mL  (74.51  mM;  Need  ultrasonic)

储存条件：2-8℃

注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(35篇)

35. [IF=3.8] Jialu Shen et al."Insights into inhibitory mechanisms: Unraveling the structure-activity relationship of dietary flavonoids on gut bacterial β-glucuronidase."Journal of Functional Foods.2024 Nov;122:106510

34. [IF=4.3] Yang Linlin et al."Spraying methyl jasmonate before harvesting can significantly increase the content of icariin in an important leaf medicinal herb, Epimedium sagittatum, by activating the expression of genes involved in flavonoid synthesis pathways."BMC

33. [IF=6.7] Xinguang Liu et al."Screening effective-component compatibility from Jinshui Chenfei formula for silicosis treatment by serum-pharmacochemistry and feedback system control."PHYTOMEDICINE.2025 Mar;138:156419

32. [IF=4.4] Chen Yangfeng et al."In Vitro evaluation of the anti-pancreatic cancer activity of epimedium herb."Frontiers in Pharmacology.2024 Jul;15:

31. [IF=4.9] Zheyuan Shen et al."Rapid evaluation of the quality of Epimedium with different processing degrees by E-eye and NIR spectroscopy combined with machine learning."MICROCHEMICAL JOURNAL.2024 Oct;205:111181

30. [IF=3.8] Ali Nasir et al."In situ growth of dual-responsive polymer as coating for open tubular capillary electrochromatographic separation of epimedins."ANALYTICAL AND BIOANALYTICAL CHEMISTRY.2024 Jun;:1-10

29. [IF=5.4] Yi-min Liu et al."Uncovering the key pharmacodynamic material basis and possible molecular mechanism of extract of Epimedium against liver cancer through a comprehensive investigation."JOURNAL OF ETHNOPHARMACOLOGY.2023 Dec;317:116765

28. [IF=5.572] Zhen Zhao et al."An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro."FOOD AND CHEMICAL TOXICOLOGY.2023 Jun;176:

27. [IF=6.208] Jiaqi Zhang et al."The Effect of Epimedium Isopentenyl Flavonoids on the Broiler Gut Health Using Microbiomic and Metabolomic Analyses."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(8):7646

26. [IF=6.352] Lin Yu et al."Highly efficient bioconversion of icariin to icaritin by whole-cell catalysis."Microbial Cell Factories.2023 Dec;22(1):1-11

25. [IF=6.208] Yu Yao et al."A Novel 3-O-rhamnoside: 2″-O-xylosyltransferase Responsible for Terminal Modification of Prenylflavonol Glycosides in Epimedium pubescens Maxim.."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(24):16050

24. [IF=1.698] Jinyan Wu et al."Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS."International Journal of Analytical Chemistry.2022 Oct 15;2022:142380

23. [IF=5.988] Qihan Luo et al."Chang qing formula ameliorates colitis-associated colorectal cancer via suppressing IL-17/NF-κB/STAT3 pathway in mice as revealed by network pharmacology study."Frontiers in Pharmacology.2022; 13: 893231

22. [IF=4.996] Yuan Jie et al."Systematic characterization of the components and molecular mechanisms of Jinshui Huanxian granules using UPLC-Orbitrap Fusion MS integrated with network pharmacology."Scientific Reports.2022 Jul;12(1):1-24

21. [IF=5.988] Li  Pin et al."Epimedium koreanum Nakai–Induced Liver Injury—A Mechanistic Study Using Untargeted Metabolomics."Frontiers in Pharmacology.2022 Jul;0:2288

20. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177

19. [IF=3.361] Yuhao Zhang et al."An integrated approach for structural characterization of Gui Ling Ji by traveling wave ion mobility mass spectrometry and molecular network."Rsc Adv. 2021 Apr;11(26):15546-15556

18. [IF=3.757] Congyan Liu et al."Enhanced hydrolysis and antitumor efficacy of Epimedium flavonoids mediated by immobilized snailase on silica."Process Biochem. 2019 Nov;86:80

17. [IF=4.36] Kun Shi et al."Epimedii Folium and Curculiginis Rhizoma ameliorate lipopolysaccharides-induced cognitive impairment by regulating the TREM2 signaling pathway."J Ethnopharmacol. 2022 Feb;284:114766

16. [IF=4.411] Zhenxian Qin et al."A Widely Metabolomic Analysis Revealed Metabolic Alterations of Epimedium Pubescens Leaves at Different Growth Stages."Molecules. 2020 Jan;25(1):137

15. [IF=4.545] Yan-dan Zhou et al."Icariin ameliorates cisplatin-induced cytotoxicity in human embryonic kidney 293 cells by suppressing ROS-mediated PI3K/Akt pathway."Biomed Pharmacother. 2019 Jan;109:2309

14.  兰海,刘欣妍,余玲,莫诺兰,张燕,郭子右,吴清.大孔树脂纯化淫羊藿中朝藿定与淫羊藿苷工艺研究[J].中草药,2020,51(17):4473-4481.

13.  许婷,黄萌萌,李瑞云,杨茹,刘丽芳,陈彦.多基原淫羊藿不同部位质量评价研究[J].中草药,2020,51(01):190-196.

12.  吴嫣艳,任会旭,冯友龙,张莉,张妤琳.安神补脑胶囊HPLC指纹图谱与3种成分含量测定方法研究[J].广东药科大学学报,2020,36(06):778-783.

11.  彭静, 马益华, 陈彦,等. 固定化蜗牛酶同时生物转化淫羊藿中4种黄酮苷[J]. 中成药, 2016, 38(9):1984-1990.

10.  高霞, 陈彦, 王莹,等. 糊精湿法制粒对淫羊藿总黄酮酶解的影响[J]. 中成药, 2014, 36(007):1392-1397.

9.  高霞, 刘璇, 陈彦,等. 淫羊藿总黄酮的生物转化过程分析[J]. 中国中药杂志, 2013, 38(23):4079.

8.  刘聪燕, 高霞, 陈彦,等. 淫羊藿总黄酮在骨质疏松大鼠体内的药动学行为[J]. 中成药, 2017, 39(008):1595-1600.

7.  刘聪燕, 高霞, 黄萌萌,等. 淫羊藿总黄酮仿生酶解肠溶胶囊的制备及评价[J]. 中草药, 2016(20).

6.  张燕. 大孔吸附树脂分离纯化淫羊藿EF5黄酮[J]. 北方药学, 2015, 000(011):11-13.

5.  李婧,王英哲,刘玉翠,景志贤,闫莉,郭俊杰,姜大成,肖井雷.地理环境因子对朝鲜淫羊藿黄酮类成分空间分布影响的探测分析[J].中国中药杂志,2019,44(24):5368-5374.

4.  刘聪燕  高霞  陈彦 等. 仿生酶解肠溶胶囊提高淫羊藿总黄酮口服生物利用度的可行性研究[J]. 中国医药工业杂志  2016(9期):1158-1164.

3.  王英哲 姜大成 容路生 肖井雷 张强 翁丽丽.东北产朝鲜淫羊藿中黄酮类成分的对比分析[J].药物分析杂志 2019 39(11):2034-2040.

2.  洪雅丹  张凌风  潘娉娉 等. HPLC法同时测定淫羊藿-骨碎补药对中7种成分[J]. 中成药  2019  041(006):1316-1321.

1.  杨茹  刘聪燕  许婷 等. 5种大孔吸附树脂对淫羊藿总黄酮的吸附特性考察[J]. 中国实验方剂学杂志  2020  v.26(06):121-128.

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